产品名称 EZClick™ Stearoylated Protein Assay Kit (FACS/Microscopy), Red Fluorescence from BIOVISION, INC.
产品货号 K418-100
产品价格 现货询价,电话:010-67529703
产品规格 100 assays
产品品牌 BIOVISION, INC.
产品概述
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Product NameEZClick™ Stearoylated Protein Assay Kit (FACS/Microscopy), Red Fluorescence
DescriptionStearoylation is one of the numerous types of post-translational modification in proteins. Stearoylated proteins are involved in the regulation of cellular processes such as apoptosis, growth and metabolism. In this modification Stearic acid, a saturated fatty acid is covalently bound to a protein through the action of long-chain-fatty-acid-[acyl-carrier-protein] ligase. In the presence of ATP, ligase then transfers a Stearate moiety to the target protein forming a carbon-sulfur bond (C=S). Recent studies showed a possible correlation between mitochondrial dysfunction and some diseases including neurodegenerative disease, cancer and aging. Furthermore, it is known that stearoylated Transferrin Receptor (TfR1) inhibits JNK activation thereby reducing mitofusin ubiquitination and restoring mitochondrial function. Studying stearoylation of proteins can shed a light on disease etiology and prevention. BioVision offers EZClick™ Stearoylated Protein Assay Kit, a highly specific, simple and robust method for labeling and detection of Stearoylated proteins. The kit uses Alkynyl Stearic Acid that is fed directly into the cells and gets incorporated into proteins during or post translation. This modification can be followed by click reaction with an azide-containing dye. The assay kit offers a powerful method for imaging localization, trafficking, and dynamics of Stearoylated proteins or detection by FACS for quantitative studies. Labeled stearoylated proteins can be directly detected in 1D or 2D gels using the appropriate excitation sources or enriched by immunoprecipitation with biotin-azide or antibodies prior to proteomic analysis. We provide sufficient materials for 100 assays in a 96-well plate format.
Size100 assays
Concentrationn/a
Applicationsfor labeling and detection of Stearoylated proteins
Other NamesStearoylated Protein Assay Kit, EZClick™ Stearoylated Protein Assay (FACS/Microscopy), Red, EZClick™ Stearoylated Protein Kit (FACS/Microscopy), EZClick™ Stearoylated Protein Assay Kit, Red, Stearoylated Protein Assay Kit, Red, EZClick™ Stearoylated Protein Assay (FACS/Microscopy), EZClick™ Stearoylated Protein Assay Kit
Gene, Accession, CAS #n/a
Catalog #K418-100
Price
Order / More InfoEZClick™ Stearoylated Protein Assay Kit (FACS/Microscopy), Red Fluorescence from BIOVISION, INC.
Product Specific Referencesn/a
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