| 产品详情 |
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| Product Name | Human CellExp™ Gremlin / GREM1, Human recombinant |
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| Description | Gremlin is also known as Cysteine knot superfamily 1, BMP antagonist 1 (CKTSF1B1), DAN domain family member 2 (DAND2), Down-regulated in Mos-transformed cells protein (DRM), Increased in high glucose protein 2 (IHG-2), Cell proliferation-inducing gene 2 protein (PIG2) or Gremlin-1 (GREM1), which is highly expressed in small intestine, fetal brain and colon. Gremlin / GREM-1 interacts with SLIT1 and SLIT2 in a glycosylation-dependent manner. Gremlin may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Gremlin down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of mono |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | GREM1, CKTSF1B1, DAND2, DRM, PIG2 |
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| Gene, Accession, CAS # | Grem1, Gene ID: 23892, Accession: O70326 |
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| Catalog # | P1124-10 |
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| Order / More Info | Human CellExp™ Gremlin / GREM1, Human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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