产品详情 |
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Antigenic Specificity | BRD3-BD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.5 mg/ml |
Applications | Western blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect BRD3-BD2 in human samples. The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. BRD3 binds hyper-acetylated chromatin and plays a role in the regulation of transcript |
Immunogen | Recombinant human BRD3-BD2 protein (Cat # 7257) |
Other Names | KIAA0043, RING3L |
Gene, Accession # | Gene ID: 8019, Accession: Q15059 |
Catalog # | 6662-100 |
Price | |
Order / More Info | BRD3-BD2 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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