产品名称 DERP-1 Antibody from DENDRITICS SAS
产品货号 DDX0210
产品价格 现货询价,电话:010-67529703
产品规格 100µg/50µg
产品品牌 DENDRITICS SAS
产品概述
产品详情
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Antigenic SpecificityDERP-1
CloneH.AK6.A3.F4
Host SpeciesHuman
Reactive Specieshouse dust mite
IsotypeIgG1 k
Formatpurified
Size100µg/50µg
Concentrationn/a
ApplicationsELISA, WB, biopanning
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DescriptionHouse-dust mite allergy belongs to the most common allergies worldwide which affect more than 50% of all allergic patients. House dust mite allergens play an important role in inducing IgE-mediated sensitization and the development of bronchial hyper responsiveness and asthma, perennial rhinitis, and atopic dermatitis. Allergic patients' sera (IgE) recognize the house-dust mite Dermatophagoides pteronyssinus Der p 1 and Der p 2. The key event in these reactions is the cross-linking of IgE antibodies on effector cells by allergens, which induces a release of biologically active mediators like histamine and leukotrienes leading to different symptoms of allergy. Studies in vivo have shown that the cysteine peptidase activity of group 1 house dust mite allergens contributes to their allergenicity. (Chapman MD, 1980; J. Immunol., 125: 587-592; Hales BJ, Thomas WR., 1997; Clin. Exp. Allergy, 27(8):868- 875; Doull IJ. et al, 1997; Allergy, 52,220; Custovic A, 1996; J. Allergy Clin. Immunol., 98: 64-72; Szalai K. et al., 2008; Mol. Immunol. 45:5, 1308-17)
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #DDX0210
Price
Order / More InfoDERP-1 Antibody from DENDRITICS SAS
Product Specific Referencesn/a
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