产品详情 |
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Antigenic Specificity | BAFF-R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.5 mg/ml |
Applications | Western blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BAFF-R Antibody. Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activ |
Immunogen | Synthetic peptide surrounding amino acid 159 of mouse BAFF-R |
Other Names | TNFRSF13C, CD268, BAFF-R, MGC138235 |
Gene, Accession # | Gene ID: 72049, Accession: Q9D8D0 |
Catalog # | 3578R-100 |
Price | |
Order / More Info | BAFF-R Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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