| 产品详情 |
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| Product Name | CAL-101 (GS-1101) |
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| Description | CAL-101 is a cell-permeable inhibitor of the PI3K catalytic subunit p110δ (IC50 = 2.5 nM) that displays 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and 89 nM for p110α, β, and γ, respectively). It has also been shown to inhibit the chemotaxis of chronic lymphocytic leukemia cells and to downregulate the secretion of chemokines triggered by B-cell receptor signaling. MW: 415.42. Purity >98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-?fluoro-?3-?phenyl-?2-?[(1S)-?1-?(9H-?purin-?6-?ylamino)propyl]-?4(3H)-?quinazolinone; Idealisib |
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| Gene, Accession, CAS # | CAS: 870281-82-6 |
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| Catalog # | 2613-5 |
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| Order / More Info | CAL-101 (GS-1101) from BIOVISION, INC. |
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| Product Specific References | n/a |
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