| 产品详情 |
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| Antigenic Specificity | Smac/DIABLO |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot, Immunohistochemistry |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Smac/DIABLO Antibody. Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/caspase-9 pathway. Smac/DIABLO binds to IAPs (Inhibitor of Apoptosis Proteins) and neutralizes the inhibitory effect of IAPs. Analysis of the structural basis of Smac/DIABLO has revealed that the N-terminal amino acids are required for Smac/DIABLO to bind to IAPs and activation of caspases. |
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| Immunogen | Synthetic peptide surrounding amino acid 220 of mouse Smac/DIABLO |
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| Other Names | SMAC, SMAC3, DIABLO, DIABLO-S , FLJ10537, FLJ25049, 0610041G12Rik |
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| Gene, Accession # | Gene ID: 66593, Accession: Q9JIQ3 |
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| Catalog # | 3298-100 |
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| Price | |
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| Order / More Info | Smac/DIABLO Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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