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| Product Name | Human CellExp™ VEGF 165, Human Recombinant |
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| Description | Vascular Endothelial Growth Factor (VEGF) plays a key role in tumor angiogenesis in many cancers. The VEGF family consists of seven secretory glycoproteins: VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, VEGF-F and Placental Growth Factor (PlGF). The binding of VEGF and its receptors leads to activation of the PI3K/AKT, p38 MAPK, FAK and paxillin. VEGFA/VEGF165 is a heparin-binding protein, which exists as a disulfide-linked homodimer. It induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Diseases associated with VEGFA/VEGF165 include microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. It is also related to the integrated Breast Cancer Pathway |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF, MGC70609. |
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| Gene, Accession, CAS # | VEGFA, Gene ID: 7422, Accession: P15692 |
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| Catalog # | 6485-10 |
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| Order / More Info | Human CellExp™ VEGF 165, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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