| 产品详情 |
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| Product Name | GW 4869 dihydrocloride |
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| Description | GW 4869 is a cell-permeable, non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 µM), but does not affect acid sphingomyelinase activity. It inhibits TNF-α-mediated sphingomyelin hydrolysis (100% inhibition at 20 µM) and TNF-α-induced cell death in MCF7 cells without interfering with activation of NF-κB or glutathione depletion in response to TNF. MW: 577.5. Purity ≥90% |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,?3'-?(1,?4-?phenylene)bis[N-?[4-?(4,?5-?dihydro-?1H-?imidazol-?2-?yl)phenyl]-?2-?propenamide, dihydrochloride; GW69A; GW554869A |
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| Gene, Accession, CAS # | CAS: 6823-69-4 |
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| Catalog # | 2417-5 |
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| Order / More Info | GW 4869 dihydrocloride from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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