| 产品详情 |
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| Product Name | CRID3 sodium salt |
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| Description | Potent NLRP3 inflammasome inhibitor; inhibits IL-1β (IC50 = 7.2 nM), IL-1α (IC50 = 12-18 nM) and IL-18 (IC50 = 10.3 nM) production. Selective for NLRP3 inflammasome over NLRC4 inflammasome and Toll-like receptor signaling. Inhibits inflammasome activation by soluble and crystalline NLRP3 stimuli. Reduces severity of experimental autoimmune encephalomyelitis, skin inflammation and airway inflammation in mice. Also glutathione S-transferase omega 1 inhibitor. Orally bioavailable. Purity 98%. MW (observed): 426.46 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt. CP-456773, MCC 950 |
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| Gene, Accession, CAS # | CAS: 256373-96-3 |
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| Catalog # | 5479/10 |
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| Price | |
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| Order / More Info | CRID3 sodium salt from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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