产品详情 |
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Antigenic Specificity | ANPEP/CD13 |
Clone | 505CT12.1.2 |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG2a |
Format | Protein G purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western blot. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal Antibody to detect ANPEP/CD13 in human samples. CD13, or aminopeptidase N, is a type II transmembrane glycoprotein that is expressed on most cells of Myeloid origin, including monocytes, basophils, eosinophils, neutrophils and Myeloid leukemias. CD13 is also found on certain epithelial cells, fibroblasts and osteoclasts. CD13 acts as a zinc-binding metalloprotease that plays a role in digestion and may function in the inactivation of some regulatory peptides such as enkephalins. CD13 may play a role in the invasion of cancer cells by enhancing their invasive capacity and metastatic behavior. The activity of CD13 can be inactivated using specific inhibitors that evoke apoptosis of CD13-positive cancer cells. Basic fibroblast growt |
Immunogen | This ANPEP/CD13 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from human ANPEP/CD13. |
Other Names | ANPEP; APN; CD13; PEPN; Aminopeptidase N; Alanyl aminopeptidase, Aminopeptidase M, Microsomal aminopeptidase |
Gene, Accession # | Gene ID: 290, Accession: P15144 |
Catalog # | 6794-100 |
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Order / More Info | ANPEP/CD13 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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