| 产品详情 |
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| Product Name | Human CellExp™ PD-1 /PDCD1, mouse recombinant |
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| Description | Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 is an immune checkpoint and guards against autoimmunity through a dual mechanism of promoting apoptosis in antigen-specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (anti-inflammatory, suppressive T cells). PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon tre |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | PDCD1, PD1, CD279, SLEB2, PD-1, PD-l |
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| Gene, Accession, CAS # | PDCD1, Gene ID: 18566, Accession: Q02242 |
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| Catalog # | 7499-50 |
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| Order / More Info | Human CellExp™ PD-1 /PDCD1, mouse recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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