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Product Name | Human CellExp™ CD273 / B7-DC / PD-L2, human recombinant |
Description | Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 23.4 kDa. The predicted N-terminus is Leu 20. DTT-red |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | PDL2, PD-L2, Butyrophilin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2 |
Gene, Accession, CAS # | PDCD1LG2, Gene ID: 80380, Accession: Q9BQ51 |
Catalog # | 7369-50 |
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Order / More Info | Human CellExp™ CD273 / B7-DC / PD-L2, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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