产品详情 |
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Antigenic Specificity | CD100 |
Clone | A8 |
Host Species | Mouse |
Reactive Species | human, African green, baboon, cynomolgus, rhesus |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD100. CD100, a 150 kD homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells. |
Immunogen | Human PHA activated lymphocytes |
Other Names | Sema4D |
Gene, Accession # | Gene ID: 10507 |
Catalog # | 328401 |
Price | |
Order / More Info | CD100 Antibody from BIOLEGEND |
Product Specific References | n/a |
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