产品详情 |
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Antigenic Specificity | CD100 |
Clone | BMA-12 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IHC-F, IP, ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD100 (SEMA4D). CD100, also known as Semaphorin-4D (SEMA4D), is a 150 kD, type I transmembrane protein, with one sema domain and one C2-type Ig domain. It is found as a homodimer on the cell surface. CD100 is expressed in the brain, kidney, heart, the majority of hematopoietic cells, and some malignant cells. CD100 is a potent inducer of angiogenesis and inhibitor of bone formation, and plays a role in lymphocyte activation, antibody production, dendritic cell maturation, and axon guidance. Its ligands are CD72 and Plexin-B1. CD100 is cleaved from the membrane of activated T and B cells, producing a soluble form. |
Immunogen | Mouse CD100-Fc fusion protein |
Other Names | Neuroimmune semaphorin 4D, Sema4D, M-Sema G, Semaphorin-C-like 2, Semaphorin-J, Semaj, Semcl2, Coll-4, Semacl2, BMA12 |
Gene, Accession # | Gene ID: 20354 |
Catalog # | 147601 |
Price | |
Order / More Info | CD100 Antibody from BIOLEGEND |
Product Specific References | n/a |
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