产品详情 |
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Antigenic Specificity | Cathepsin E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.5 mg/ml |
Applications | Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of Cathepsin E in human samples. Cathepsin E (EC: 3.4.23.34) (CTSE) is an intracellular gastric aspartyl protease. It was originally identified as a cathepsin D-like acid protease. It is active in acidic conditions in a pH range from 2.5 to 5.5. In vitro experiments have identified several CTSE substrates including insulin beta chain, neurokinin, and FGF. Although the function of CTSE is not completely understood, it has been implicated in several physiological and pathological processes. CTSE is required for antigen presentation on class II MHC molecules. CTSE-deficient macrophages show abnormalities such as autophagy. Like many other cathepsins, CTSE has emerged as a therapy target for cance |
Immunogen | Human recombinant Cathepsin E (Cat. No. 7842) |
Other Names | Cathepsin E form I, Cathepsin E form II, CTSE, |
Gene, Accession # | Gene ID: 1510, Accession: P14091 |
Catalog # | A1709-100 |
Price | |
Order / More Info | Cathepsin E Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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