| 产品详情 |
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| Antigenic Specificity | Bad |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat, monkey |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot, Immunoprecipitation, Immunohistochemistry |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bad Antibody. The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bad) apoptosis. Similar to other family member, Bad also exhibits sequence homology to Bcl-2. Bad can selectively dimerize with Bcl-xL and Bcl-2, but not with Bax, Bcl-xs, Mcl-1, or itself. In mammalian cells, Bad binds more strongly to Bcl-xL than Bcl-2. This may explain why Bad reverse the death repressor activity of Bcl-xL, but not that of Bcl-2 |
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| Immunogen | Synthetic peptide surrounding amino acid 115 of mouse Bad |
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| Other Names | BBC6, BCL2L8, Bcl-2-binding component 6, Bcl-2-like 8 protein |
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| Gene, Accession # | Gene ID: 2493288, Accession: Q61337.1 |
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| Catalog # | 3030-100 |
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| Price | |
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| Order / More Info | Bad Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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