| 产品详情 |
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| Product Name | KN-62 |
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| Description | Cell-permeable. KN-62 is a selective inhibitor of Ca?+/calmodulin-dependent kinase type II (CaMKII; IC50= 900 nM). It binds directly to the calmodulin binding site of the enzyme. It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM). MW: 721.84. Purity ≥98% |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-?[(2S)-?2-?[(5-?isoquinolinylsulfonyl)methylamino]-?3-?oxo-?3-?(4-?phenyl-?1-?piperazinyl)propyl]phenyl ester,? 5-?isoquinolinesulfonic acid |
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| Gene, Accession, CAS # | CAS: 127191-97-3 |
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| Catalog # | 2495-1 |
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| Order / More Info | KN-62 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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