| 产品详情 |
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| Product Name | Recombinant Human β-NGF (Animal-Free) |
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| Description | β-NGF is a pluripotent mediator and it exists in many tissues. Secreted β-NGF can bind to tryosine kinase A receptor with higher affinity and to p75 (NTR) with low affinity. β-NGF is well known as an endogenous neurotrophic factor involved in the embryonal development, survival, and regeneration of mammalian sympathetic and sensory neurons. In adults, β-NGF is also involved in the survival and regeneration of neurons in the central nervous system. Involvement of β-NGF in the immune system has also been reported. In vitro cultured B lymphocyte can constitutively secret β-NGF, which can act as an autocrine growth and differentiation factor for B cells. β-NGF can also downregulate the production of IFN-γ by T cells. Recombinant β-NGF has been used in many clinical trials to treat different disease including Alzheimer's disease, diabetic polyneuropathy, and HIV-associated peripheral neuropathy. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Nerve growth factor, NGF, beta-NGF, b-NGF |
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| Gene, Accession, CAS # | Gene ID: 4803 |
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| Catalog # | 711906 |
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| Order / More Info | Recombinant Human β-NGF (Animal-Free) from BIOLEGEND |
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| Product Specific References | n/a |
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