| 产品详情 |
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| Product Name | MI-nc (hydrochloride) |
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| Description | Purity ≥98%. MW: 405.36. MI-nc (hydrochloride) is a weak inhibitor of the menin-MLL interaction. Menin is a tumor suppressor protein. Menin is a part of the MLL (Mixed Lineage Leukemia) SET1-like histone methyl transferase complex. Association of menin with MLL fusion proteins causes oncogenic transformation. MI-nc (hydrochloride) showed very weak inhibition of the menin-MLL interaction (IC50 = 193 µM) in vitro. It serves as a negative control for MI-2 which is a potent menin-MLL interaction inhibitor (IC50 = 0.45 µM). |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MI-nc, 6-ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]-thieno[2,3-d]pyrimidine,dihydrochloride |
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| Gene, Accession, CAS # | CAS: 1934302-23-4 |
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| Catalog # | B2816-1 |
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| Price | |
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| Order / More Info | MI-nc (hydrochloride) from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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