产品名称 GAD65 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-79293
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityGAD65
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size100 µg
Concentrationlyophilized
ApplicationsImmunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL
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DescriptionGAD65 Polyclonal Antibody. Antibodies to glutamic acid decarboxylase-65 (GAD65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.
Immunogenn/a
Other NamesGlutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, GAD2, GAD65
Gene, Accession #Entrez: 14417, 24380, 2572; Uniprot: P48320, Q05329, Q05683
Catalog #PA5-79293
Price
Order / More InfoGAD65 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料