产品名称 PD-1 Antibody from INVITROGEN ANTIBODIES
产品货号 MA5-15781
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPD-1
Clone12A7D7
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatpurified
Size100 ug
Concentrationn/a
ApplicationsImmunohistochemistry: 2.5 µg/mL, Western Blot: 1 µg/mL
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPD-1 Monoclonal Antibody (12A7D7). Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of ``danger signals'' such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and
Immunogenn/a
Other NamesCD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, programmed cell death protein 1, protein PD-1
Gene, Accession #Entrez: 18566, 301626, 5133; Uniprot: Q02242, Q15116
Catalog #MA5-15781
Price
Order / More InfoPD-1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料