产品名称 PD-L1/CD274 Antibody from BOSTER BIO
产品货号 PB9994
产品价格 现货询价,电话:010-67529703
产品规格 100ug (sample available)
产品品牌 BOSTER BIO
产品概述
产品详情
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Antigenic SpecificityPD-L1/CD274
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatimmunogen affinity purified
Size100ug (sample available)
Concentration500ug/ml.
ApplicationsELISA, WB
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DescriptionRabbit IgG polyclonal Picoband™ antibody for Programmed cell death 1 ligand 1(CD274) detection. Tested with WB, ELISA in Mouse. No cross reactivity with other proteins. Programmed death-ligand 1 (PD-L1), also known as CD274 or B7-H1, is a protein that in humans is encoded by the CD274 gene. It is mapped to 9p24.1. PD-L1 is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. It has been concluded that upregulation of PD-L1 on tumor MDCs downregulates T-cell immunity and that PD-L1 blockade may represent an approach for cancer immunotherapy. Additionally, PD-L1 can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection. What's more, it has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer.
ImmunogenE. coli-derived mouse PD-L1 recombinant protein (Position: F19-T238). Mouse PD-L1 shares 78.6% amino acid (aa) sequence identity with human PD-L1.
Other NamesProgrammed cell death 1 ligand 1;PD-L1;PDCD1 ligand 1;Programmed death ligand 1;B7 homolog 1;B7-H1;CD274;Cd274;B7h1, Pdcd1l1, Pdcd1lg1, Pdl1;
Gene, Accession #Cd274, UniProt: Q9EP73
Catalog #PB9994
Price
Order / More InfoPD-L1/CD274 Antibody from BOSTER BIO
Product Specific Referencesn/a
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