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Product Name | Human CellExp™ B7-1 / CD80, mouse recombinant |
Description | B7-1 and B7-2, together with their receptors CD28 and CTLA 4, constitute one of the dominant co-stimulatory pathways that regulate T and B cell responses. Although both CTLA 4 and CD28 can bind to the same ligands, CTLA 4 binds to B7 1 and B7 2 with a 20 100 fold higher affinity than CD28 and is involved in the down regulation of the immune response. B-lymphocyte activation antigen B7-1 (referred to as B7) also known as cluster of Differentiation 80 (CD80), is a member of cell surface immunoglobulin superfamily and is expressed on activated B cells, activated T cells, macrophages and dendritic cells. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA- 4 (for at |
Size | 10 µg |
Concentration | n/a |
Applications | RUO |
Other Names | CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 |
Gene, Accession, CAS # | Cd80, Gene ID: 12519, Accession: Q00609 |
Catalog # | P1075-10 |
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Order / More Info | Human CellExp™ B7-1 / CD80, mouse recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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