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| Product Name | Human CellExp™ B7-2 /CD86, human recombinant |
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| Description | Cluster of Differentiation 86 (CD86) also known as B-lymphocyte activation antigen B7-2, is a type I membrane protein that is a member of the immunoglobulin superfamily. It is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be upregulated through interferon γ. CD86 is the ligand for two proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD86 and CD80 together prime T cells. B7-2 was shown to promote the generation of mature APC (antigen presenting cells) |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CD86, B7-2, B70, CD28LG2, LAB72, MGC34413 |
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| Gene, Accession, CAS # | CD86, Gene ID: 942, Accession: P42081 |
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| Catalog # | 7496-50 |
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| Order / More Info | Human CellExp™ B7-2 /CD86, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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