产品名称 CD366 (TIM3) Antibody from INVITROGEN ANTIBODIES
产品货号 14-5871-82
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityCD366 (TIM3)
Clone8B.2C12
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG1, kappa
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsFlow Cytometry: 0.25 µg/test, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent
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DescriptionCD366 (TIM3) Monoclonal Antibody (8B.2C12), eBioscience™. TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmun
Immunogenn/a
Other NamesHAVCR2,TIM-3
Gene, Accession #Entrez: 171285; Uniprot: Q8VIM0
Catalog #14-5871-82
Price
Order / More InfoCD366 (TIM3) Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 15905494, 16709797, 17855338, 20819927, 22168579, 22685601, 25172495, 26026061, 28345650
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