| 产品详情 |
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| Product Name | PRMT1, human recombinant (Active) |
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| Description | PRMT1 methylate's (mono & asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-rich domain (may methylate HNRNPA1 and histones) methylate's SUPT5H. The PRMT1 protein functions as a histone methyltransferase specific for H4. PRMT1 is an essential factor in oncogenesis and is a potential novel therapeutic target in cancer. PRMT1-mediated methylation serves as a positive modulator of IR/IRS-1/PI3K pathway and glucose uptake in skeletal muscle cells. CAF1 is a new regulator of PRMT1-dependent arginine methylation. PRMT1 arginine-methylate's MRE11 therefore it regulates the activity of MRE11-RAD50-NBS1 complex during the intra-S-phase DNA damage checkpoint response. PRMT1 plays a post-translatio |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Protein arginine N-methyltransferase 1, Histone-arginine N-methyltransferase PRMT1, Interferon receptor 1-bound protein 4, Histone-arginine N-methyltransferase PRMT1, Interferon receptor 1-bound protein 4 |
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| Gene, Accession, CAS # | ANM1, Gene ID: 3276, Accession: Q99873 |
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| Catalog # | 4865-1000 |
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| Order / More Info | PRMT1, human recombinant (Active) from BIOVISION, INC. |
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| Product Specific References | n/a |
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