产品名称 GNF 5837 from TOCRIS BIOSCIENCE
产品货号 4559/10
产品价格 现货询价,电话:010-67529703
产品规格 10 mg
产品品牌 TOCRIS BIOSCIENCE
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Product NameGNF 5837
DescriptionPotent pan-Trk inhibitor. Displays antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively). Exhibits selectivity for Trk receptors over a range of kinases, with some activity at PDGFR and c-Kit (IC50 values are 0.87 and 0.91 μM respectively). Orally bioavailable. Purity 98%. MW (observed): 535.49
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesN-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Gene, Accession, CAS #CAS: 1033769-28-6
Catalog #4559/10
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Order / More InfoGNF 5837 from TOCRIS BIOSCIENCE
Product Specific ReferencesPubMed: 28604807
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