| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human IL-13 (carrier-free) |
|---|
| Description | Human IL-13 was initially cloned from cDNA libraries of activated T cells. IL-13 is an immunoregulatory cytokine secreted predominantly by activated T(H)2 cells, and it is a key mediator in the pathogenesis of allergic inflammation. IL-13 shares many functional properties with IL-4, and they share a common receptor subunit, the alpha subunit of the IL-4 receptor (IL-4Ralpha). IL-13 mediates its effects by interacting with a complex receptor system comprised of IL-4Ralpha and two IL-13 binding proteins, IL-13Ralpha1 and IL-13Ralpha2. Ligation of the IL-13 receptor complex results in signaling via the insulin receptor substrate (IRS)-1 and 2 and STAT-6 pathways. IL-13, like IL-4, is a cytokine produced by T(H)2 type helper T cells in response to signaling through the T cell antigen receptor and by mast cells and basophils upon cross-linkage of the high-affinity receptor for immunoglobulin E (IgE). IL-13 has been implicated in airway hypersensitivity and mucus hypersecretion, inflammatory bowel disease, and parasitic nematode expulsion. |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | BA |
|---|
| Other Names | Interleukin-13, NC30 |
|---|
| Gene, Accession, CAS # | Gene ID: 3596 |
|---|
| Catalog # | 571106 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human IL-13 (carrier-free) from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|