产品名称 ML 218 hydrochloride from TOCRIS BIOSCIENCE
产品货号 4507/10
产品价格 现货询价,电话:010-67529703
产品规格 10 mg
产品品牌 TOCRIS BIOSCIENCE
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Product NameML 218 hydrochloride
DescriptionSelective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in an in vivo rat model of Parkinson's disease. Displays no significant inhibition of L- or N-type calcium channels, Kir6 (KATP) or KV11.1 (hERG) potassium channels. Orally active. Purity 99%. MW (observed): 405.79
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide hydrochloride
Gene, Accession, CAS #CAS: 1346233-68-8
Catalog #4507/10
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Order / More InfoML 218 hydrochloride from TOCRIS BIOSCIENCE
Product Specific ReferencesPubMed: 27596273, 28573241
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