产品名称 Nerve Growth Factor Receptor (NGFR) (Cytoplasmic Domain) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN350709
产品价格 现货询价,电话:010-67529703
产品规格 100 µL
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityNerve Growth Factor Receptor (NGFR) (Cytoplasmic Domain)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formatserum
Size100 µL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC),Western Blotting (WB)
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DescriptionFunction: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.Subunit: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. Interacts with ARMS and NTRK1. Can form a ternary complex with NTRK1 and ARMS and this complex is affected by the expression levels of ARMS. An increase in ARMS expression leads to a decreased association of NGFR and NTRK1. Interacts with LINGO1.Subcellular location: Membrane, Single-pass type I membrane protein. Also known as: Low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR, p75, LNGFR, p75NTR, RNNGFRR.
ImmunogenA synthetic peptide from the cytoplasmic domain of human p75NTR (low affinity NGF receptor, p75, LNGFR, p75NTR) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in many other species including mouse and rat.
Other Namesngfr|wu:fb38c02|wu:fc10h01|CD271|Gp80-LNGFR|TNFRSF16|p75(NTR)|p75NTR|LNGFR|RNNGFRR|Tnfrsf16|p75|NRH1b|fullback|nrh1|p75ntr|tnfrsf16|p75NGFR
Gene, Accession #Gene ID: 4804,18053,24596
Catalog #ABIN350709
Price
Order / More InfoNerve Growth Factor Receptor (NGFR) (Cytoplasmic Domain) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 10514511, 14966521, 8627329, 10544233, 3022937, 9915784, 11244088
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