产品详情 |
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Antigenic Specificity | BACE1 |
Clone | BA0250 |
Host Species | Recombinant Rabbit |
Reactive Species | mouse, rat, human |
Isotype | IgG |
Format | purified |
Size | n/a |
Concentration | n/a |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-BACE1 Recombinant Antibody (BA0250). This product is a rabbit antibody that recognizes BACE1. The antibody BA0250 can be used for immunoassay techniques such as: IP, WB. This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. Vassar et al. (1999) found that transient overexpression of BACE did not affect APP expression, but decreased alpha-secretase cleavage and increased beta-secretase activity in cells expressing wildtype or Swedish mutant (104760.0008) APP. BACE overexpression induced cleavage only at the known beta-secretase positio |
Immunogen | Synthetic peptide from Human BACE1 |
Other Names | Beta-Site APP-Cleaving Enzyme 1; Membrane-Associated Aspartic Protease 2; Beta-Site APP Cleaving Enzyme 1; Aspartyl Protease 2; EC 3.4.23.46; Memapsin-2; Asp 2; BACE; ASP2; Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme; Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1; Transmembrane Aspartic Proteinase Asp2; Beta-Secretase 1 Precursor Variant 1; Beta-Site APP-Cleaving Enzyme; APP Beta-Secretase; EC 3.4.23; KIAA1149; HSPC104 |
Gene, Accession # | Gene ID: 23621, UniProt: P56817 |
Catalog # | CBMAB-0115CQ |
Price | |
Order / More Info | BACE1 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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