产品名称 Alpha2, 6-Sialyltransferase Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN927272
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityAlpha2, 6-Sialyltransferase
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB)
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DescriptionThe histopathological picture of Alzheimer's disease is characterized by senile plaques and neurofibrillary tangles, and because the senile plaques form first, they are considered the initial lesion. Senile plaques are known to be formed by accumulation of betaamyloid peptide (Abeta). Abeta peptide is produced by the cleavage of amyloid precursor protein (APP) by two types of proteolytic enzymes. The first cleavage is performed by betasecretase (BACE1), and the second gamma secretase. It is thought that their inhibitors may be capable of serving as safe drugs for the treatment of Alzheimer's disease. In recent years a glycosyltransferase involved in the biosynthesis of sugar chains (alpha 2, 6 sialyltransferase) has also been shown to be cleaved by BACE1. The cleavage site was identified at the same time, and as a result it was demonstrated that in rats it produces cleavagedtype alpha 2, 6 sialyltransferase (E41 Form). Description: Serum.
Immunogenalpha 2,6 sialyltransferase antibody was raised in rabbit using a synthetic peptide for a part of Rat a2, 6 ialyltransferase (E41 Form) as the immunogenSerum
Other Namesalpha-2, 6-Sialyltransferase , alpha-2, 6-Sialyltransferase , Alpha 2.6-ST 1 , ST6Gal 1 , SIAT1 , B-Cell antigen CD75 , Sialyltransferase 1 , ST6N .
Gene, Accession #n/a
Catalog #ABIN927272
Price
Order / More InfoAlpha2, 6-Sialyltransferase Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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