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| Product Name | Gelatinase (Gelatin Degradation/Zymography) Assay Kit (Fluorometric) |
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| Description | Gelatinases are a type of matrix zinc-dependent metalloproteases (MMPs) that degrade gelatins and a variety of other extracellular matrix proteins. These enzymes are synthesized as latent zymogens that are activated by proteolysis and inhibited by tissue inhibitors of metalloproteases (TIMPs). Two mammalian gelatinases, Gelatinase A (MMP-2) and Gelatinase B (MMP-9), are critical for basement membrane degradation and are highly upregulated in variety of tumor cells. Gelatinase activity is usually detected by small peptide-based activity assays which may suffer from lack of substrate specificity. Other methods for gelatinase activity include gelatin Zymography where samples are electrophoresed on a gelatin-containing SDS-PAGE, and further ren |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | • Measurement of gelatinase activity• For screening/studying/characterizing gelatinase inhibitors |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K444-100 |
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| Order / More Info | Gelatinase (Gelatin Degradation/Zymography) Assay Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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