产品名称 TRIP10/CIP4 Antibody from INVITROGEN ANTIBODIES
产品货号 A301-186A
产品价格 现货询价,电话:010-67529703
产品规格 100 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityTRIP10/CIP4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size100 µL
Concentrationn/a
ApplicationsImmunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000
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DescriptionTRIP10/CIP4 Polyclonal Antibody. Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention
Immunogenn/a
Other NamesCdc42-interacting protein 4, Protein Felic, Salt tolerant protein, hSTP, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP-10, TRIP10, CIP4, STOT, STP
Gene, Accession #Entrez: 106628, 9322; Uniprot: Q15642, Q8CJ53
Catalog #A301-186A
Price
Order / More InfoTRIP10/CIP4 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
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