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| Product Name | Human CellExp™ Insulin R / CD220, Human Recombinant |
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| Description | Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulin-binding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulin-like growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1. MW: 106. |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | INSR, Insulin receptor, IR, CD220 |
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| Gene, Accession, CAS # | IRS1, Gene ID: 3667, Accession: P06213-2 |
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| Catalog # | P1377-50 |
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| Price | |
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| Order / More Info | Human CellExp™ Insulin R / CD220, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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