| 产品详情 |
| Edit |   |
|---|
| Product Name | Human CellExp™ LAIR1 / CD305, Fc Tag, Human Recombinant |
|---|
| Description | Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is constitutively expressed on the majority of human peripheral blood mononuclear leukocytes. LAIR-1 or CD305 is a transmembrane glycoprotein with a single immunoglobulin-like domain and a cytoplasmic tail containing two immune receptor tyrosine-based inhibitory motifs. LAIR-1 recruits SHP-1 and SHP-2 phosphatases upon activation, and cross-linking of the LAIR-1 antigen on natural killer (NK) cells results in strong inhibition of NK cell-mediated cytotoxicity. Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and act |
|---|
| Size | 10 µg |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | LAIR1, CD305 |
|---|
| Gene, Accession, CAS # | LAIR1, Gene ID: 3903, Accession: Q6GTX8 |
|---|
| Catalog # | P1239-10 |
|---|
| Price | |
|---|
| Order / More Info | Human CellExp™ LAIR1 / CD305, Fc Tag, Human Recombinant from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|