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| Product Name | K48-linked Di-Ubiquitin |
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| Description | Poly-ubiquitylation of target proteins through linkage at K48, is now the most thoroughly studied of the various chain linkages, and was once considered the hallmark of this post-translational modification. It is now clear that many, if not all, poly-Ub chain topologies likely play distinct and important roles in regulating cellular processes. Nevertheless, K48 linkage remains a critical pathway for the cells to maintain homeostasis through proteolytic degradation, and as such remains very intriguing for the study of DUBs that play a role in the degradation, as well as the proteasome itself. These di-ubiquitin chains are generated from the enzymatic linkage (E2-25K) of wild-type ubiquitin through lysine 48. The most distal ubiquitin contain |
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| Size | 50 µg |
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| Concentration | 2.5 mg/ml |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 6415-50 |
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| Price | |
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| Order / More Info | K48-linked Di-Ubiquitin from BIOVISION, INC. |
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| Product Specific References | n/a |
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