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| Product Name | Lyn B, Active |
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| Description | Lyn is a 56 kd tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck and the v-yes protein as well as to the gene products of v-fgr and v-src. Northern hybridization analysis showed that a 3.2-kilobase Lyn mRNA was expressed in a variety of tissues of the human fetus (1). Lyn is expressed preferentially in B cells and can be coimmunoprecipitated with IgM suggesting that Lyn is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction (2). Crosslinking of membrane-bound IgM with antibody induces rapid increase in activities of Lyn and Lyn-associated phosphatidylinositol 3-kinase (3). Crosslinking of B-cell antigen receptor also induces association of Lyn with an 85 |
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| Size | 5 µg |
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| Concentration | 5µg/50 µl |
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| Applications | RUO |
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| Other Names | Lyn B |
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| Gene, Accession, CAS # | Lyn B, Gene ID: 4067, Accession: BC059394 |
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| Catalog # | 7715-5 |
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| Order / More Info | Lyn B, Active from BIOVISION, INC. |
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| Product Specific References | n/a |
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