产品名称 UBDX1 (full length and short isorform) Antibody from ALDEVRON FREIBURG GmbH
产品货号 GM-0804
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ALDEVRON FREIBURG GmbH
产品概述
产品详情
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Antigenic SpecificityUBDX1 (full length and short isorform)
Clone5C3-1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatpurified
Size100 µg
Concentrationn/a
Applicationswestern blotting, immunoprecipitation, immunifluorescence
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Descriptionp97 is a highly abundant and conserved member of the AAA family of ATPase. It has been termed an ubiquitin selective chaperone as it functions within the ubiquitin and/or proteasome pathway. p97 does not interact with ubiquitinated substrates on its own, but requires specific adapters that interact with ubiquitinated substrates and p97 and recruits p97 to substrates. One family of adapters contains a UBX domain, which has been shown with certain adapters to function as a p97-binding module. UBXD1 is a UBX domain containing protein and p97 adapter. This adapter is unique in that it does not harbor an ubiquitin association domain and binds p97 via its PUG domain (another p97 binding motif). Two isoforms of UBXD1 are produced in cells, a full-length form of approximately 54 kDa, and an alternatively spliced variant that lacks the amino-terminal translational start site, and encodes a 47 kDa protein that is derived from an internal translational initiation site. UBXD1 expression at the RNA level has been shown to trend lower in poor prognostic cancers, including those of the breast and prostate.
ImmunogencDNA
Other Namesn/a
Gene, Accession #n/a
Catalog #GM-0804
Price
Order / More InfoUBDX1 (full length and short isorform) Antibody from ALDEVRON FREIBURG GmbH
Product Specific Referencesn/a
产品资料