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Product Name | Cystathionine β Synthase Inhibitor Screening Kit (Fluorometric) |
Description | Cystathionine β Synthase (EC 4.2.1.22, CβS) is a Pyridoxal 5-Phosphate-dependent enzyme that uses cysteine and homocysteine as substrates to catalyze the formation of H2S and cystathionine. CβS is well-known for its role in human sulfur metabolism. The overexpression of CβS has been implicated in Down Syndrome, and also results in homocystinuria; or low levels of homocysteine in blood. Homocystinuria leads to a mutli-systemic disorder of the connective tissue, muscles, and central nervous system (CNS). For that reason, pharmacological inhibitors of human CβS present attractive therapeutic potential in order to restore baseline CβS activity and blood homocysteine levels. It has been shown that aminooxyacetic aci |
Size | 100 assays |
Concentration | n/a |
Applications | • Screening and characterization of inhibitors of Cystathionine β Synthase (CβS) |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | K695-100 |
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Order / More Info | Cystathionine β Synthase Inhibitor Screening Kit (Fluorometric) from BIOVISION, INC. |
Product Specific References | n/a |
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