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| Product Name | IGFBP-6 ELISA |
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| Description | The Eagle Biosciences IGFBP-6 ELISA assay is based on polyclonal antibodies and recombinant IGFBP-6, expressed in eukaryotic cells. This kit for IGFBP-6 (E112) is a so-called Sandwich-Assay. It utilizes two specific antibodies of high affinity. First the IGFBP-6 in the sample binds to the immobilized antibody on the microtiter plate. In a two-step sequence, the biotin-conjugated anti-IGFBP-6-Antibody and the streptavidin-peroxidase are bound. Subsequently, the peroxidase catalyzes an enzymatic reaction resulting in a blue coloration. The intensity of the blue color depends on the analyte content of the sample. The reaction is stopped by the addition of stop solution and color intensity (yellow) is quantified by measuring the absorption. Sample Types: serum, plasma, biological fluids. Range: 0.1 - 10 ng/ml. Sensitivity: 0.026 ng/mL. Time: 3 hours • The Insulin-like Growth Factor 6 (IGFBP-6) is part of the IGF-System which consists of several binding proteins (1-6) and IGF-I and -II. The Insulin-like Growth Factors are involved in the control of human growth and regulated themselves by their binding proteins. The IGFBPs show high amino acid sequence homology, they have conserved N- and C-terminal domains which are involved in IGF-binding. In contrast the central linker region is highly variable. This region is not directly involved in IGF-binding but influences stability and localisation of the IGFBP / IGF complex and can be modified by glycosylation and phosphorylation. |
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| Size | 1 x 96 well |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 6 IGFBP IGFBP-6 IGFBP6 E112 112 ASSAY EIA ELISA GROWTH IGF IMMUNOASSAY INSULIN INSULIN-LIKE KIT mediagnost Insulin like Insulin-like Growth Factor binding protein |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E112 |
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| Order / More Info | IGFBP-6 ELISA from EAGLE BIOSCIENCES INC. |
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| Product Specific References | n/a |
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