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| Product Name | Recombinant Human CXCL11 (ITAC) (carrier-free) |
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| Description | CXCL11 is a CXC chemokine lacking the ELR (Glutamate-Leucine-Arginine) tripeptide motif, which is functionally and structurally related to CXCL9 and CXCL10. CXCL11, together with CXCL9 and CXCL10, specifically binds to the G protein-coupled receptor CXCR3 and is involved in chemotaxis of immune cells and angiogenesis. Expression of both CXCR3 and CXCL11 by the Th1-associated cytokine IFNγ creates an amplification loop of cell-mediated immune response between Th1 cells. CXCR7 has been identified as an alternate receptor for CXCL11 and is involved in growth, survival, and adhesion of tumor cells. |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Interferon-inducible T-cell alpha chemoattractant (ITAC); Small inducible cytokine, subfamily B, member 9B (SCYB9B); Small inducible cytokine, subfamily B, member 11 (SCYB11) |
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| Gene, Accession, CAS # | Gene ID: 6373 |
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| Catalog # | 574908 |
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| Order / More Info | Recombinant Human CXCL11 (ITAC) (carrier-free) from BIOLEGEND |
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| Product Specific References | n/a |
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