产品名称 AIFM1 Antibody from ATGen
产品货号 ATGA0411
产品价格 现货询价,电话:010-67529703
产品规格 100ul, 50ul
产品品牌 ATGen
产品概述
产品详情
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Antigenic SpecificityAIFM1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, k
Formatpurified
Size100ul, 50ul
Concentrationn/a
ApplicationsELISA, WB, ICC/IF
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionApoptosis-inducing factor 1, also known as AIFM1, is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. AIFM1 has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIFM1 from mitochondria, but not to block its apoptogenic activity. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy.
ImmunogenRecombinant human AIFM1 (98-609aa) purified from E. coli
Other NamesApoptosis-inducing factor 1 mitochondrial isoform 2 precursor, Apoptosis-inducing factor 1, mitochondrial isoform 2 precursor, AIF, CMTX4, COWCK, COXPD6, PDCD8
Gene, Accession #NP 665811
Catalog #ATGA0411
Price
Order / More InfoAIFM1 Antibody from ATGen
Product Specific Referencesn/a
产品资料