| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Alix |
|---|
| Clone | 3A9 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse, and frog |
|---|
| Isotype | IgG1, κ |
|---|
| Format | purified |
|---|
| Size | 25 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot (WB), Immunofluorescence Microscopy (IF), IP |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-Alix. Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. The predicted molecular weight is approximately 96 kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interact with multiple cellular Alix-binding partners that are involved in apoptotic induction, endosomal sorting, and endocytosis. The Bro1 domain interacts with CHMP4b, which is also involved in endosomal sorting. |
|---|
| Immunogen | Recombinant full-length human Alix protein |
|---|
| Other Names | PDCD6IP, PDCD6 interacting protein, AIP1, Hp95 |
|---|
| Gene, Accession # | Gene ID: 10015 |
|---|
| Catalog # | 634501 |
|---|
| Price | |
|---|
| Order / More Info | Alix Antibody from BIOLEGEND |
|---|
| Product Specific References | PubMed: 23364798,25535287 |
|---|
| 产品资料 |
|
|