| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Allergin-1 |
|---|
| Clone | TX83 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG1, κ |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 25 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PE anti-mouse Allergin-1. Allergin-1, also known as mast cell Ag-32, is a 60 kD single pass transmembrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain in the extracellular region and one immunoreceptor tyrosine-based inhibitory motif (ITIM)-like domain in the cytoplasmic region. Allergin-1 is expressed on mast cells, dendritic cells, and macrophages as well as at low levels on neutrophils. After tyrosine phosphorylation, allergin-1 recruits PTPN6, PTPN11, and INPP5D, which results in a diminution of IgE-mediated degranulation in mast cells. No ligands have been identified for this molecule. |
|---|
| Immunogen | Transfected cells expressing allergin-1-Flag |
|---|
| Other Names | Allergy inhibitory receptor 1 (Allegrin1), Mast cell Ag-32 (MCA-32, MCA32), Milr1 |
|---|
| Gene, Accession # | Gene ID: 380732 |
|---|
| Catalog # | 141805 |
|---|
| Price | |
|---|
| Order / More Info | Allergin-1 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|