| 产品详情 |
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| Antigenic Specificity | Alpha-II Spectrin |
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| Clone | D8B7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | unconjugated |
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| Size | 200 µl |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC-P, ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Anti-Alpha-II Spectrin. The spectrins are a family of widely distributed cytoskeletal proteins which are involved in actin crosslinking. Spectrin α-chain heterodimerizes with tissue-specific β-chains. It is specifically expressed in nonerythrocytic cells. The protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in the gene are the cause of early infantile epileptic encephalopathy. Fodrin, a spectrin that seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus a candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
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| Immunogen | Clone D8B7 was developed against the alpha II spectrin SH3 domain |
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| Other Names | Spectrin alpha chain, brain, alpha-II spectrin, fodrin alpha chain, spectrin, non-erythroid alpha chain, SIG-39702-200 |
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| Gene, Accession # | Gene ID: 6709 |
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| Catalog # | 803201 |
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| Price | |
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| Order / More Info | Alpha-II Spectrin Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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