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Product Name | β-Lapachone |
Description | Cell-permeable. A DNA topoisomerase I inhibitor. Unlike Camptothecin (Cat. No. 1039), β-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1. Also acts as a histone demethylase inhibitor selective to JMJ2DE (IC50 =3.6 µM). MW: 242.27. Purity ≥98% by TLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione |
Gene, Accession, CAS # | CAS: 4707-32-8 |
Catalog # | 2262-25 |
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Order / More Info | β-Lapachone from BIOVISION, INC. |
Product Specific References | n/a |
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