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| Product Name | WDR5 0103 |
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| Description | WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM). It inhibits the catalytic activity of MLL core complex in in vitro experiments with IC50 of 39 µM. WDR5 is a component of mixed lineage leukemia (MLL) that targets histone-3 and in vitro data shows interaction of WDR5-0103 with MLL inhibits MLL core complex methyltransferase activity. However WDR5-0103 has no effect on other methyltransferases. MW: 383.44. Purity ≥98% by HPLC |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)benzoic acid methyl ester |
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| Gene, Accession, CAS # | CAS: 890190-22-4 |
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| Catalog # | B1125-50 |
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| Order / More Info | WDR5 0103 from BIOVISION, INC. |
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| Product Specific References | n/a |
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