产品名称 ABCG5 Antibody from BOSTER BIO
产品货号 PB9415
产品价格 现货询价,电话:010-67529703
产品规格 100ug (sample available)
产品品牌 BOSTER BIO
产品概述
产品详情
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Antigenic SpecificityABCG5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted: chicken)
Isotypen/a
Formatimmunogen affinity purified
Size100ug (sample available)
Concentration500ug/ml.
ApplicationsWB
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DescriptionRabbit IgG polyclonal Picoband™ antibody for ATP-binding cassette sub-family G member 5(ABCG5) detection. Tested with WB in Human. No cross reactivity with other proteins. ABCG5 (Atp-binding cassette, subfamily g, member 5) also known as STEROLIN 1, is a protein that in humans is encoded by the ABCG5 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. The ABCG5 gene contains 13 exons and spans about 28 kb. The ABCG5 gene is mapped on 2p21. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. Small (2003) reviewed the role of ABC transporters in secretion of cholesterol from liver into bile, particularly the role of ABCG5/ABCG8. The ABCG5 and ABCG8 genes are an example of closely neighboring genes in a head-to-head orientation that, when mutated, cause the same phenotype.
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human ABCG5 (197-221aa ERRRVSIAAQLLQDPKVMLFDEPTT), different from the related mouse and rat sequences by two amino acids.
Other NamesATP-binding cassette sub-family G member 5;Sterolin-1;ABCG5;
Gene, Accession #ABCG5, UniProt: Q9H222
Catalog #PB9415
Price
Order / More InfoABCG5 Antibody from BOSTER BIO
Product Specific Referencesn/a
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